After KAUST Academy
Almokhtar started a second Master's degree in September 2026, this time in Bioscience at KAUST, focusing on cell and molecular biology within KAUST BioMed.
Summer project
Bioinformatics Specialization · Cohort 2026
From a CRISPR Screen to Therapeutic Vulnerabilities: Functional Genomics of Tamoxifen Sensitisation in ER+ Breast Cancer
This project reanalysed a genome-wide CRISPR knockout screen together with four independent transcriptomic datasets to identify genes whose loss increases tamoxifen efficacy in ER+ breast cancer, and to assess which of those candidates carry the least predicted risk of adding to the musculoskeletal symptoms that drive patients to discontinue endocrine therapy. Individual candidate genes did not replicate across datasets, while pathway-level biology replicated in all four, and no candidate proved superior on both halves of the question. All thresholds were fixed and the candidate list frozen before validation data were opened.
With KAUST Academy
- Cohort 2026
University of Cambridge · Bioinformatics Summer Program
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