بعد أكاديمية كاوست
Saad is a medical student at the University of Tabuk as of October 2026.
المشروع الصيفي
تخصص المعلوماتية الحيوية · دفعة 2025
Identifying Differentially Expressed Genes Shared Between Progressive Types of Multiple Sclerosis to Uncover Drivers of Disease Progression
This project aims to identify differentially expressed genes shared between the progressive forms of Multiple Sclerosis (MS); Primary Progressive MS (PPMS) and Secondary Progressive MS (SPMS) to better understand the molecular mechanisms driving disease progression. A bulk RNA-seq transcriptomic analysis was conducted using publicly available brain tissue data (GEO accession: GSE290552). The data were analyzed using DESeq2, with pairwise comparisons between MS subtypes. Venn diagrams were used to identify and visualize genes uniquely shared between the progressive types. To further interpret the biological relevance of these findings, a literature review was conducted to investigate the potential roles of the identified genes in the context of Multiple Sclerosis.
المشرف: Hugo Tavares, Andries J. van Tonder
مع أكاديمية كاوست
- دفعة 2025
جامعة كامبريدج · البرنامج الصيفي للمعلوماتية الحيوية
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